Your GLP-1 Stomach Problems Aren’t “Just Side Effects.” A Gastroenterologist Reveals the Upstream Protocol That’s Giving Women Their Digestion Back—Without Touching Their Dose.
The constipation, the sulfur burps, the cement-in-your-stomach feeling—none of it has to be the price you pay for losing weight. Here’s why everything you’ve been told to try was aimed at the wrong organ.
Women on Ozempic, Wegovy, and Mounjaro should be celebrating. Instead, they’re sitting in my office trying not to cry.
If you haven’t had a real bowel movement in over a week… if sulfur burps are ruining meals, car rides, and time with your grandkids… if your stomach feels like you swallowed concrete after every meal… and your doctor told you to drink water and try Miralax…
I need you to know something.
I’m Dr. Rebecca Marsh, a board-certified gastroenterologist with 14 years of practice focused on motility disorders. In the last three years, I’ve treated over 2,000 women on GLP-1 medications. And I’m watching the same thing happen to nearly every one of them.
They come in with a medicine cabinet full of laxatives. They’ve done everything their prescribing doctor suggested. Nothing is working. And most of them say some version of the same sentence:
“But I’ve lost the weight. So I just deal with it.”
They shouldn’t have to. And after seeing patient after patient accept this as normal, I won’t stay quiet about what’s actually going on—or what actually fixes it.
Every Laxative You’ve Tried Was Aimed at the Wrong Organ
You may already know your GLP-1 medication slows your stomach down. That’s actually how it helps with weight loss—food stays longer, you feel full.
But here’s what your prescribing doctor probably didn’t explain: the constipation, the sulfur gas, and the bloating aren’t three separate side effects. They’re one problem compounding itself.
When the stomach slows, food ferments. Fermentation produces sulfur gas—that’s the rotten-egg burps. But here’s the part I didn’t fully understand until I tracked it across hundreds of patients: the gas itself causes the stomach to distend, which triggers MORE slowing. It’s a feedback loop. Slow stomach creates gas. Gas stretches the stomach. Stretched stomach slows further. Every day you don’t break the cycle, the cycle gets tighter.
Your instincts were right. You weren’t dramatic. You weren’t “not drinking enough water.” Your stomach was stuck in a loop that no amount of Miralax could touch—because Miralax doesn’t reach your stomach. None of them do.
The Three-Pathway Protocol I Now Put Every GLP-1 Patient On
Once the feedback loop was clear, the solution was obvious. You don’t break a cycle by treating the end of it. You address all three pathways—at the source—at the same time.
That’s the protocol I now recommend to every GLP-1 patient who walks through my door. And a company called Motilli built the exact formula into a daily gummy.
Here’s what’s in it and why each piece matters:
Celery Juice Concentrate (Apigenin)
This targets the vagus nerve signal that tells your stomach to contract and move food through. GLP-1 medications quiet that signal. Apigenin helps wake it back up. Think of it as restarting the rhythm your medication slowed down.
Chlorophyllin
This binds directly to hydrogen sulfide—the specific compound causing sulfur burps. It neutralizes the gas before it ever rises. My patients usually notice the burps fading within the first week. That alone changes their willingness to eat in public again.
Soluble Prebiotic Fiber
This is the piece that makes me angriest at my own profession. Every doctor tells GLP-1 patients to “eat more fiber.” Almost none of them specify WHICH KIND. Insoluble fiber adds bulk. In a system that’s already backed up, that’s like adding more cars to a traffic jam. Soluble prebiotic fiber does the opposite—it softens and lubricates what’s stuck without creating more volume.
“Three pathways. Wake up the stomach. Kill the sulfur. Soften what’s stuck. All working on the same organ that every laxative in your cabinet ignores.”
“Eleven days without going. Miralax twice a day. Nothing. Two weeks on Motilli and I’m regular again for the first time since starting Ozempic. I actually cried in my bathroom. My husband thought something was wrong.”
Linda T., 56
“The sulfur burps were destroying me. I couldn’t ride in the car with my daughter without her cracking the window. A week and a half in—gone. Just gone. Still on Mounjaro. Still losing weight. But I can eat dinner with my family again without wanting to disappear.”
Sharon W., 49
“I tried Colace, Dulcolax, MiraLAX, mag citrate, two different fiber supplements, and Smooth Move tea. None of them helped because none of them were working on my stomach. Motilli was. Three weeks in and the cement feeling is finally lifting. I wish my GI doctor had known about this.”
Diane M., 62
What 90 Days Actually Looks Like—Across 2,000 Patients
One person’s story is powerful. But I’ve watched this play out across thousands of women in my practice. Here’s the pattern I see again and again:
Days 3-7
The sulfur burps start fading. This is usually the first thing patients report. One woman told me she ate garlic bread at an Italian restaurant for the first time in four months and didn’t spend the rest of the night apologizing to her husband.
Weeks 2-3
The cement feeling lifts. Patients describe waking up and realizing their stomach feels… normal. Not empty. Not bloated. Just normal. Several have told me they forgot what that felt like. Bowel movements start becoming more regular—not forced, not urgent, just happening the way they’re supposed to.
Weeks 4-6
This is where the real shift happens. The feedback loop is broken. The stomach is moving again, so fermentation drops, so gas drops, so distension drops, so the stomach moves even better. The same cycle that was destroying their digestion starts working in reverse. Patients stop tracking. They stop planning around their symptoms. They just… live.
Months 2-3
Patients tell me they forgot what the problem felt like. Their partners notice. One husband told his wife she seemed “lighter”—not in weight, in mood. A patient’s daughter called my office to say thank you because her mom came to Thanksgiving dinner for the first time in two years without leaving the table early.
That last one is why I still practice medicine.
My own mother started Mounjaro eight months ago. Lost 22 pounds. Developed every symptom I just described. I put her on the same protocol. She texts me every Sunday now—not about her stomach. About what she cooked for dinner. That silence is the result.
Why I Recommend Motilli Specifically
I don’t endorse supplements. In 14 years of practice, I’ve recommended maybe three. Most of what’s on the market is either underdosed, poorly sourced, or built for a problem that doesn’t match the actual mechanism.
Motilli is the first I’ve seen that addresses all three upstream pathways in one formula at clinical dosing. Specifically:
Targets the stomach—not the colon like every laxative on the shelf
Combines all three pathways so you’re breaking the full feedback loop, not just one piece of it
Gummy format—easy to take even when your stomach is already rebelling against swallowing anything
Available without a prescription—ships direct so you’re not waiting six weeks for a specialist appointment
“It’s what I give my own mother. That’s not something I say lightly.”
The Cost of Waiting Isn’t What You Think
I have to be direct with you about something. Every month the feedback loop continues, the gastric slowdown digs in deeper. I’ve seen women who caught this at month two bounce back in weeks. I’ve seen women who waited a year need three times as long to restore normal motility.
This isn’t a scare tactic. It’s biology. A stomach that’s been stuck in a slowing loop for months develops patterns that are harder to reverse than one that’s been stuck for weeks. The earlier you break the cycle, the faster it breaks.
Motilli offers a 90-day money-back guarantee. Use it for the full three months. If your digestion doesn’t come back—if the sulfur doesn’t fade, the cement feeling doesn’t lift, and your bowel movements don’t normalize—you get every cent back.
So the real question isn’t whether to try it. It’s what happens if you don’t.
You can keep taking Miralax that doesn’t reach your stomach. Keep enduring the sulfur burps. Keep telling yourself the suffering is the price of the weight loss.
Or you can address the actual problem—at the actual organ—with the actual protocol that’s working for thousands of women who were exactly where you are right now.
“Your GLP-1 prescription should have included a plan for your stomach. It didn’t. Now it can.”
We Could Sell Out Tomorrow… Or Maybe Even Today
And once that happens…
Once we do run out of stock…
It could take weeks—even months—to get back in because each bottle of Motilli requires precision manufacturing and quality testing that can’t be rushed.
So if you’re serious about breaking the feedback loop, addressing all three upstream pathways, and finally getting your digestion back without touching your dose…
I recommend you DO NOT leave this page.
Because this may be your only chance to get Motilli and finally understand why every laxative in your cabinet was aimed at the wrong organ.
If you’re still reading this, that means we still have stock available. Otherwise, this page would already be offline.
But we can’t guarantee how much longer that will be the case.
I’ve watched too many women suffer through something that has a solution. Don’t be the next one who waits.
Try Motilli Risk-Free for 90 Days
Three pathways. One gummy. Wake up the stomach. Kill the sulfur. Soften what’s stuck. All working upstream where your laxatives can’t reach.
90-Day Money-Back Guarantee.
No dose changes. No prescriptions. Just results.
Motilli is a dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any new supplement, especially if you are on GLP-1 medications.